Phytochemical Analysis, Antimicrobial and Antioxidant Activity of Crude Extracts from Selected Medicinal Plants.

Authors

  • Sandipty Kayastha Central Department of Biotechnology, Tribhuvan University.
  • Mitesh Shrestha Molecular Biotechnology Unit, Nepal Academy of Science and Technology.
  • Hemanta Kumari Chaudhary Center for Molecular Dynamics Nepal.
  • Krishna Kumar Shrestha Ethnobotanical Society of Nepal
  • Krishna Das Manandhar Central Department of Biotechnology, Tribhuvan University.
  • Bal Hari Poudel Central Department of Biotechnology, Tribhuvan University.

DOI:

https://doi.org/10.55530/ijmbiosnepal.v2i3.30

Keywords:

Medicinal Plants, Phytochemical Analysis, Crude Extracts, Ficus religiosa

Abstract

Background: The search for potential natural bioactive compounds has been carried out for a long time. Researchers working in the field of natural product chemistry are starting to realize the importance of ethnomedicinal knowledge.
Methodology: The aim of this study was to carry out preliminary analysis of different plants to understand their therapeutic potential.To this end, methanolic extracts were prepared from four different plant specimens. ntimicrobial, antioxidant and cytotoxicity assays were carried out at different concentrations of the extracts.
Results: The highest percentage yield by methanol extraction was achieved from Sapindus murokosii. Phytochemical analysis detected presence of different types of secondary metabolites present in these species. Among the plants selected, Ficus religiosa showed the highest quantity of phenolics and flavonoids content along with lowest IC50 and LC50 for anti-oxidant activity and cytotoxicity assay respectively.
Conclusion: The results obtained leads to the conclusion that the selected plants might be possessing strong therapeutics which can be further analyzed for isolation and identification of bioactive compounds.

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Published

2017-06-30

How to Cite

Kayastha, S. ., Shrestha, M., Chaudhary, H. K. ., Shrestha, K. K. ., Manandhar, K. D., & Poudel, . B. H. . (2017). Phytochemical Analysis, Antimicrobial and Antioxidant Activity of Crude Extracts from Selected Medicinal Plants. International Journal of Medicine and Biomedical Sciences, 2(3), 1–7. https://doi.org/10.55530/ijmbiosnepal.v2i3.30

Issue

Vol. 2 No. 3 (2017): June

Section

ORIGINAL ARTICLE

License

Copyright (c) 2017 International Journal of Medicine and Biomedical Sciences

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